A Poké Ball (Japanese: モンスターボール Monster Ball) is a type of item that is critical to a Trainer's quest, used for catching and storing Pokémon. Both a general term used to describe the various kinds as well as a specific term to refer to the most basic among these variations, Poké Balls are ubiquitous in the modern Pokémon world. Up to six Pokémon can be carried with a Trainer in Poké Balls, while any number of other Poké Balls can be held in the Bag for later use. These six Pokémon in the Poké Balls can be attached to the user's belt for carrying them around. Some Pokémon do not like to be carried around in Poké Balls, such as Sigma's Sableye.

The strength of a Poké Ball is determined by how much it raises a wild Pokémon's catch rate, and may in fact vary depending on the conditions of the battle. Poké Balls limit the power of Pokémon contained inside, taming them, though they do not cause the Pokémon inside to always obey the Trainer. The invention of Poké Balls apparently occurred in the Johto region, where Apricorns grow; these fruit were cut apart and carved out, then fitted with a special device, and used to catch wild Pokémon prior to the mass production of the Balls that occurs in modern times under Silph Co. and the Devon Corporation. Some Trainers still use Poké Balls made from Apricorns, while Kurt, a resident of Azalea Town, still constructs them. In the games, Drayden claims that Poké Balls did not exist during his childhood; however, due to Poké Balls being in the sunken ship in A Shipful of Shivers, it is implied that in the anime, Poké Balls were first made at least 300 years ago.